Table listing Gastrointestinal and Central Nervous System adverse events. Reference: 2.

Adverse Events2
Nausea 7%
Vomiting 3%
Dry mouth 3%
Epigastric distress 1%
Constipation Less than 1%
Dizziness and light-headedness 5%
Drowsiness 4%
Headache 2.5%
Tiredness, nervousness, insomnia, confusion Less than 1%

The most common adverse events for Motofen (≥2%) are nausea, vomiting, dry mouth, dizziness and light-headedness, drowsiness, and headache. Constipation was reported in <1% of patients, indicating that it produces an antidiarrheal effect without causing constipation often seen with other antidiarrheal agents.

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